The Dark Side of Malignant Pleural Mesothelioma

Malignant pleural mesothelioma is the most common form of mesothelioma, which is a cancer affecting the mesothelium. Only around 3000 total mesothelioma cases are reported a year in the United States and the pleural form accounts for three-fourths of it. It affects the pleura, which is the lining that protects the lungs. The pleura is constructed with two membranous layers to shores up the lungs and shields the lung cavity. While the outer layer guards the chest cavity and diaphragm, the inner one called the visceral layer encompasses the lungs. Pleural mesothelioma usually attacks one of these layers initially but may spread to the other layer too. The cancer is invariably caused by the asbestos particles trapped in the spaces available between mesothelium cells after being inhaled.

After settling down in convenient places, the particles trigger chemical reactions causing the cells to divide in a lawless manner. The activity thickens the pleural layers and mesothelical cells and a fluid build-up called pleural effusion occurs. The extra fluid presses the lungs thereby preventing easy breathing. The cancer is heralded by persistent dry cough, emission of blood through coughing, problems with swallowing, shortness of breath, weight loss of inexplicable nature, fatigue, lump formation around the chest etc.

Diagnosing pleural mesothelioma is fraught with dangers because these symptoms can be the result of other diseases like pneumonia and influenza too. It requires proper examination of the medical history of the patient, imaging tests like CT scan, MRI, X-ray and biopsy to establish the type and class of the cancer.

Conventional treatments for malignant pleural mesothelioma are surgery, chemotherapy and radiotherapy. If the problem is so acute, doctors may combine two or all of these for pull off better effects. But mesothelioma prognosis is not always desirably bright because most cases are detected only at highly progressed stages. If diagnosed at the initial stage itself, the patient has more chances of survival.

Being caused by asbestos exposure, malignant pleural mesothelioma patients have the legal rights to claim for compensation from the parties who are directly responsible. The compensation amount may run into millions in some cases.

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